One of the miniatures of the manuscript Harley 4431 depicts the death of Hero. When Hero discovers the lifeless body of her beloved Leander in the sea of Sestos, she leaps from the battlements of her castle to follow him to the hereafter.

The miniature is taken from “The Epistle of Othea” ("L'Épître Othéa"), a work by French poet and author Christine de Pisan (1363–1430), which is included in the manuscript known as "The Book of the Queen" along with various other works. It is an allegorical story in the form of a letter written by Othea (goddess of wisdom and prudence) to the Trojan hero Hector. It narrates episodes from classical mythology in an effort to give them a greater spiritual and moral dimension. The manuscript miniatures that are included with the de Pisan stories were painted by an unknown French illustrator known as the "Master of the City of Ladies" (Maître de la Cité des dames).